The compound shown above is D12-PGJ2, which closely resembles delta-12-protaglandin J3, or D12-PGJ3, a compound that targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice during experiments conducted by Penn State researchers. According to the American Cancer Society, about 5,150 new cases of CML are reported annually and approximately 270 people die from the disease each year.
Credit: Sandeep Prabhu December 15, 2011
Penn State researchers Sandeep Prahbu (right) and Robert Paulson (left) sketch out a delta-12-protaglandin J3, or D12-PGJ3. The compound, derived from fish oil, targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice.
Credit: Patrick Mansell, Penn State December 15, 2011
Penn State researchers said that delta-12-protaglandin J3, or D12-PGJ3, is a promising treatment for the treatment of leukemia. The compound, which is made from fish oil, can target and kill leukemia stem cells. The team plans to conduct human trials on the compound soon.
Credit: Patrick Mansell, Penn State December 15, 2011
Sandeep Prahbu, associate professor of immunology and molecular toxicology in the department of veterinary and medical sciences, Penn State, specializes in the study of the health benefits of fish oil. He co-directed a study that discovered a treatment that uses a compound produced from fish oil to kill stem cells in chronic myelogenous leukemia, or CML, in mice. The team plans to conduct human trials soon. Credit: Patrick Mansell
Credit: Patrick Mansell December 15, 2011
Robert Paulson, associate professor of veterinary and biomedical sciences, Penn State, injects a sample into the mass spectrometer in the lab at the Henning Building on Penn State's University Park campus. The device was used in research to find a treatment for leukemia. Credit: Patrick Mansell, Penn State
Credit: Patrick Mansell, Penn State December 15, 2011
Robert Paulson, associate professor of veterinary and biomedical sciences at Penn State, examines a sample in a lab on the University Park campus. Paulson, who specializes in the study of leukemia, co-directed the research on using a compound made from fish oil as a way to treat leukemia.
Credit: Patrick Mansell, Penn State December 15, 2011
Leukemia stem cells are unharmed by current leukemia treatments. A treatment created by a team Penn State College of Agricultural Sciences researchers was able to kill the stem cells of chronic myelogenous leukemia, or CML, in mice. CML is a type of leukemia that claims the lives of hundreds of Americans each year.
Credit: Patrick Mansell, Penn State December 15, 2011
A sample is placed in a mass spectrometer in the lab at the Henning Building on Penn State's University Park campus. The team uses the device to detect and analyze compounds in their research on possible treatments for leukemia.
Credit: Patrick Mansell, Penn State December 15, 2011
Penn State researchers initially tested a compound produced from fish oil on a type of leukemia found in mice called the Friend Virus. This slide shows a Friend Virus Leukemia Stem Cell. Learning how to target and kill leukemia stem cells is critical to finding a cure for leukemia.
Credit: Robert Paulson December 16, 2011